Expression of transcellular and paracellular calcium and magnesium transport proteins in renal and intestinal epithelia during lactation

In conclusion, proteins involved in transcellular Ca2+ and Mg2+ transport pathways increase during lactation, while expression of paracellular transport proteins remained unchanged. Increased fractional Ca2+ excretion can be explained by vitamin D-dependent intestinal hyperabsorption and bone demineralization, despite enhanced transcellular Ca2+ uptake by the kidney.

http://ajprenal.physiology.org/cgi/content/abstract/313/3/F629?rss=1

Source: AJP: Renal Physiology - September 1, 2017 Category: Urology & Nephrology Authors: Beggs, M. R., Appel, I., Svenningsen, P., Skjodt, K., Alexander, R. T., Dimke, H. Tags: RESEARCH ARTICLE Source Type: research