Elastin receptor (S-gal) occupancy by elastin peptides modulates T-cell response during murine emphysema

This study demonstrates that, during murine emphysema, EP-S-gal interactions contribute to a Th-1 and Th-17 proinflammatory T-cell response combined with a Tc-1 response. Our study also highlights the S-gal receptor as a putative pharmacological target to modulate such an immune response.

Source: AJP: Lung Cellular and Molecular Physiology - September 1, 2017 Category: Respiratory Medicine Authors: Meghraoui-Kheddar, A., Pierre, A., Sellami, M., Audonnet, S., Lemaire, F., Le Naour, R. Tags: RESEARCH ARTICLE Source Type: research