Long-term nicotine exposure dampens LPS-induced nerve-mediated airway hyperreactivity in murine airways
In conclusion, long-term nicotine exposure dampened LPS-induced AHR. The effect of nicotine was mimicked by TTX, suggesting the involvement of neuronal mechanisms. This information might be used for evaluating the long-term effects of nicotine and further exploring of how tobacco products interact with bacterial airway infections.
Source: AJP: Lung Cellular and Molecular Physiology - Category: Respiratory Medicine Authors: Xu, Y., Cardell, L.-O. Tags: RESEARCH ARTICLE Source Type: research
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