Cancer immunotherapy: Searching in the immune checkpoint black box

Nature Reviews Drug Discovery 16, 599 (2017). doi:10.1038/nrd.2017.163 Author: M. Teresa Villanueva Checkpoint blockade through inhibition of programmed cell death protein 1 (PD1), which enables tumours to evade the immune system, has radically changed the treatment and prognosis of many cancers, especially melanoma. However, a majority of patients do not respond to PD1 inhibition, and great effort
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research