SNARE proteins in membrane trafficking

Abstract
SNAREs (soluble N‐ethylmaleimide‐sensitive fusion protein attachment protein receptors) are the core machinery mediating membrane fusion. In this review, we provide an update on the recent progress on SNAREs regulating membrane fusion events, especially, the more detailed fusion processes dissected by well developed biophysical methods and in vitro single molecule analysis approaches. We also briefly summarize the relevant research from Chinese laboratories and highlight the significant contributions on our understanding of SNARE mediated membrane trafficking from scientists in China.

Synopsis
SNAREs are the core machinery mediating membrane fusion. The recent studies using biophysical methods and in vitro single molecule analysis provide mechanistic insight of fusion events mediated by SNARE proteins.

Source: Traffic - August 31, 2017 Category: Research Authors: Tuanlao Wang, Liangcheng Li, Wanjin Hong Tags: REVIEW Source Type: research