Sr2+ has low efficiency in regulating spontaneous release at the Calyx of Held synapses

This study employed cell‐attached and pre/post‐synaptic whole‐cell recording at the Calyx of Held synapse in synaptotagmin‐2 knock‐out mice and revealed that Sr2+ has higher permeability through voltage gated calcium channels and lower efficiency in regulating spontaneous neurotransmitter release than Ca2+.

Source: Synapse - August 31, 2017 Category: Neurology Authors: Shuli Zhang, Xuefeng Wang, Xiaohui Wang, Xuefeng Shen, Jianyuan Sun, Xintian Hu, Peihua Chen Tags: Research Article Source Type: research