Enhancing brown fat with NFIA

Nature Cell Biology 19, 1006 (2017).
doi:10.1038/ncb3591

Authors: Suzanne N. Shapira & Patrick Seale
Brown adipose tissue is a key metabolic organ that oxidizes fatty acids and glucose to generate heat. Through epigenomic analyses of multiple adipose depots, the transcription factor nuclear factor I-A (NFIA) is now shown to drive the brown fat genetic program through binding to lineage-specific cis-regulatory elements.

Source: Nature Cell Biology - August 31, 2017 Category: Cytology Authors: Suzanne N. Shapira Patrick Seale Tags: News and Views Source Type: research