Discrete memory impairments in largely pure chronic users of MDMA

Chronic use of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) has repeatedly been associated with deficits in working memory, declarative memory, and executive functions. However, previous findings regarding working memory and executive function are inconclusive yet, as in most studies concomitant stimulant use, which is known to affect these fu nctions, was not adequately controlled for. Therefore, we compared the cognitive performance of 26 stimulant-free and largely pure (primary) MDMA users, 25 stimulant-using polydrug MDMA users, and 56 MDMA/stimulant-naïve controls by applying a comprehensive neuropsychological test battery.

Source: European Neuropsychopharmacology - August 30, 2017 Category: Psychiatry & Psychology Authors: Michael D. Wunderli, Matthias Vonmoos, Marina F ürst, Katrin Schädelin, Thomas Kraemer, Markus R. Baumgartner, Erich Seifritz, Boris B. Quednow Source Type: research