Arsenic and Obesity: A Comparison of Urine Dilution Adjustment Methods
Conclusions:
Our findings suggest that arsenic exposure is not associated with obesity, and that urinary creatinine and osmolality may be colliders on the causal pathway from arsenic exposure to obesity, as common descendants of hydration and body composition. In studies of urinary biomarkers and obesity or obesity-related outcomes, alternative metrics such as urinary flow rate or analytic strategies such as covariate-adjusted standardization should be considered. https://doi.org/10.1289/EHP1202
Received: 07 October 2016
Revised: 21 March 2017
Accepted: 30 March 2017
Published: 28 August 2017
Address correspondence to M. Argos, University of Illinois at Chicago, 1603 W. Taylor St., MC 923, Chicago IL 60612 USA. Telephone: 312-355-1584. Email: argos@uic.edu
The authors declare they have no actual or potential competing financial interests.
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Source: EHP Research - Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
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