RGS3 inhibits TGF ‐β1/Smad signalling in adventitial fibroblasts

In conclusion, these results suggest that RGS3 may provide protection against pathological changes of AFs and the development of atherosclerosis by inhibiting TGF‐β1/Smad signalling. RGS3 may be a potential therapeutic target for atherosclerosis.

Source: Cell Biochemistry and Function - August 27, 2017 Category: Biochemistry Authors: Fang Xu, Ying Liu, Lei Shi, Hongjing Cai, Wei Liu, Yejia Hu, Yuling Li, Wendan Yuan Tags: RESEARCH ARTICLE Source Type: research