An Attempt to Establish a Common Animal Model for Hepatorenal Fibrosis in Rats.

In this study, we were able to induce significant fibrosis in the liver and early stages of fibrosis in the kidneys. The result also demonstrated that the addition of BSA conferred a liver protective effect against CCl4 induced hepatotoxicity, whereas combination of CCl4 and BSA proved to be detrimental for kidneys. PMID: 28835866 [PubMed]
Source: Pathology Research International - Category: Pathology Tags: Patholog Res Int Source Type: research