The MNS glycophorin variant GP.Mur affects differential erythroid expression of Rh/RhAG transcripts

ConclusionErythroid RhD and RhCcEe were differentially expressed at the transcript levels, which could be related to their different degrees of interaction or sensitivity to RhAG. Further, the reduction or absence of glycophorin B in GYP.Mur erythroid cells affected transcript expressions of RhAG and RhCcEe. Thus, GPB and GP.Mur differentially influenced Rh/RhAG expressions prior to protein translation.

Source: Vox Sanguinis - July 1, 2017 Category: Hematology Authors: K. Hsu, M. ‐S. Kuo, C.‐C. Yao, H.‐C. Cheng, H.‐J. Lin, Y.‐S. Chan, M. Lin Tags: Original Paper Source Type: research