Unravelling biology and shifting paradigms in cancer with single-cell sequencing

Nature Reviews Cancer 17, 557 (2017). doi:10.1038/nrc.2017.58 Authors: Timour Baslan & James Hicks The fundamental operative unit of a cancer is the genetically and epigenetically innovative single cell. Whether proliferating or quiescent, in the primary tumour mass or disseminated elsewhere, single cells govern the parameters that dictate all facets of the biology of cancer. Thus, single-cell analyses provide
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Perspectives Source Type: research