Targeting autophagy in cancer

Nature Reviews Cancer 17, 528 (2017).
doi:10.1038/nrc.2017.53

Authors: Jean M. Mulcahy Levy, Christina G. Towers & Andrew Thorburn
Autophagy is a mechanism by which cellular material is delivered to lysosomes for degradation, leading to the basal turnover of cell components and providing energy and macromolecular precursors. Autophagy has opposing, context-dependent roles in cancer, and interventions to both stimulate and inhibit autophagy have been

Source: Nature Reviews Cancer - July 28, 2017 Category: Cancer & Oncology Authors: Jean M. Mulcahy Levy Christina G. Towers Andrew Thorburn Tags: Review Source Type: research