Therapeutic resistance: Ironing it out
Nature Reviews Cancer 17, 510 (2017).
doi:10.1038/nrc.2017.71
Author: Ulrike Harjes
Since mesenchymal-like properties in cancer cells are often associated with therapy resistance, Viswanathan et al. explored vulnerabilities of these cells. They identified an enzyme of the lipid peroxidase pathway, inhibition of which caused ferroptosis in a range of cancer types.
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Ulrike Harjes Tags: Research Highlight Source Type: research
More News: Cancer | Cancer & Oncology