Therapeutic resistance: Ironing it out

Nature Reviews Cancer 17, 510 (2017). doi:10.1038/nrc.2017.71 Author: Ulrike Harjes Since mesenchymal-like properties in cancer cells are often associated with therapy resistance, Viswanathan et al. explored vulnerabilities of these cells. They identified an enzyme of the lipid peroxidase pathway, inhibition of which caused ferroptosis in a range of cancer types.
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Research Highlight Source Type: research