In vitro aggregating β-lactamase-polyQ chimeras do not induce toxic effects in an in vivo Caenorhabditis elegans model

A series of human diseases are caused by the misfolding and aggregation of specific proteins or peptides into amyloid fibrils; nine of these diseases, referred to as polyglutamine diseases, are associated with...

Source: Journal of Negative Results in BioMedicine - August 22, 2017 Category: Research Authors: Roel Van Assche, Charline Borghgraef, Jonathan Vaneyck, Mireille Dumoulin, Liliane Schoofs and Liesbet Temmerman Tags: Research Source Type: research