Myelopoiesis embraces its inner weakness
Nature Immunology 18, 953 (2017).
doi:10.1038/ni.3814
Authors: Motti Gerlic & Ben A Croker
The ability to expand and contract populations of myeloid and lymphoid cells during emergency hematopoiesis helps shape the immune response. The expression of intracellular and soluble forms of osteopontin regulates apoptosis thresholds differently in myeloid cells and lymphoid cells to counter infection.
Source: Nature Immunology - Category: Allergy & Immunology Authors: Motti Gerlic Ben A Croker Tags: News and Views Source Type: research