Heterologous Expression of Spinosyn Biosynthetic Gene Cluster in < b > < i > Streptomyces < /i > < /b > Species Is Dependent on the Expression of Rhamnose Biosynthesis Genes

This report demonstrates spinosyn production in 2Streptomyces strains and stresses the essential role of rhamnose in this process. This work also provides a potential alternative route for producing spinosyn analogs by means of genetic manipulation in the heterologous hosts.J Mol Microbiol Biotechnol 2017;27:190-198
Source: Journal of Molecular Microbiology and Biotechnology - Category: Microbiology Source Type: research