Discrepant HPV/cytology cotesting results: Are there differences between cytology ‐negative versus HPV‐negative cervical intraepithelial neoplasia?

CONCLUSIONSThere are no significant clinical or pathologic differences between NILM/HPV‐positive and ASCUS‐positive/HPV‐negative CIN‐3–positive specimens. Cytologic sampling or interpretation remains the main reason for discrepancies. However, HPV‐negative CIN‐3 with positive cytology exists and may be missed by primary HPV screening. Cancer Cytopathol 2017. © 2017 American Cancer Society.
Source: Cancer Cytopathology - Category: Pathology Authors: Tags: Original Article Source Type: research