Dose of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers and Outcomes in Heart Failure: A Meta-Analysis [Original Articles]

Conclusions
In patients with HF with reduced ejection fraction, compared with lower doses, higher doses of ACEI and ARB significantly though modestly improved the composite end point of all-cause mortality or HF hospitalization without significantly increasing the chances of discontinuation.

Source: Circulation: Heart Failure - August 8, 2017 Category: Cardiology Authors: Khan, M. S., Fonarow, G. C., Ahmed, A., Greene, S. J., Vaduganathan, M., Khan, H., Marti, C., Gheorghiade, M., Butler, J. Tags: Heart Failure Original Articles Source Type: research