Precuneus Abnormalities in Middle-Aged to Older Adults with Depressive Symptoms: An Analysis of BDI-II Symptom Dimensions

We recently reported age-related increases in left precuneus cortical thickness (CT) in older adults with elevated total depressive symptoms. However, it is unclear whether abnormalities in precuneus surface area (SA) are also evident and whether specific symptom dimensions of depression moderated age effects on these measurements. Seventy-three adults completed the Beck Depression Inventory – 2nd edition (BDI-II) and underwent structural neuroimaging. Measures of CT and SA were extracted from the right and left precuneus via FreeSurfer.

Source: Psychiatry Research: Neuroimaging - August 14, 2017 Category: Psychiatry Authors: Sarah M. Szymkowicz, Vonetta M. Dotson, Molly E. McLaren, Liselotte De Wit, Deirdre M. O'Shea, Francis T. Talty, Andrew O'Shea, Eric C. Porges, Ronald A. Cohen, Adam J. Woods Source Type: research