Hypericin cytotoxicity in tumor and non-tumor cell lines: a chemometric study
In this study, chemometric analysis was applied for the first time on photodynamic assays to investigate the cytotoxicity of HY in tumor (HEp-2) and non-tumor (Vero and HUVEC) cell lines. The experimental planning was based on eight assays using the 23 full factorial design combining three important variables for PDT: photosensitizer concentrations, incubation time of cells in HY solutions and employed light dose (=590 ±10nm).
Source: Photodiagnosis and Photodynamic Therapy - Category: Laser Surgery Authors: Joyce Laura da Silva Gon çalves, Claudia Bernal, Hidetake Imasatoa, Janice Rodrigues Perussi Source Type: research