Influence of IL ‐6, IL‐33, and TNF‐α on Human Mast Cell Activation: Lessons from Single Cell Analysis by Flow Cytometry

Conclusions: In conclusion, IL‐33, and in a lesser extent IL‐6, prime individual MCs for subsequent IgE‐mediated activation. Moreover, this priming effect is synergistic. In contrast, none of the cytokines had a priming effect on MRGPRX2‐mediated activation of MCs. This article is protected by copyright. All rights reserved.

Source: Cytometry Part B: Clinical Cytometry - July 1, 2017 Category: Molecular Biology Authors: Nathalie Cop, Didier G. Ebo, Chris H. Bridts, Jessy Elst, Margo M. Hagendorens, Christel Mertens, Margaretha A. Faber, Luc S. De Clerck, Vito Sabato Tags: Original Article Source Type: research