Dietary citrate and plasma ionized calcium: Implications for platelet donors

Conclusions: Citrus juice may lower [Ca2+] for 2‐3 hours. This could add to the effect of IV citrate infusion during platelet donation, thus worsening the expected fall in [Ca2+]. This, in turn, would likely increase the rate and severity of hypocalcemic toxicity. It is prudent to advise platelet donors to avoid high citrate anion beverages, such as citrus juice, for at least 4 hours prior to donation.

Source: Journal of Clinical Apheresis - August 1, 2017 Category: Hematology Authors: Stefanie Haynes, Elda Hickson, Jeanne Linden, Patricia St. Pierre, Paula Ducharme, Paula Sulmasy, Linda Welch, Yong Zhao, Mindy Greene, Michelle Vauthrin, Robert Weinstein Tags: RESEARCH ARTICLE Source Type: research