Detection of mycobacterial infection in non-human primates using the Xpert MTB/RIF molecular assay

Tuberculosis is a major public health concern, and diagnostic strategies applied to animal populations are scarce. As part of ongoing efforts to control tuberculosis dissemination at our animal facility, two non-human primates (NHP, Saimiri sciureus) presenting cutaneous lesions were examined for mycobacterial infection. Both animals tested positive for acid-fast bacilli and Mycobacterium tuberculosis using a molecular assay (IS6110 PCR). Animals were euthanized and several samples were tested for M.

Source: Tuberculosis - August 10, 2017 Category: Respiratory Medicine Authors: Duanne Alves da Silva, Amanda M. R êgo, Nicole V. Ferreira, Manoela A.S. de Andrade, Aline R. Campelo, Paulo César S. Caldas, Márcia Aparecida S. Pereira, Paulo Redner, Lucindo C. de Pina, Felipe C. Resende, Thalita A. Pissinatti, Claudia A.A. Lopes, T Source Type: research