Prevalence of TDP ‐43 proteinopathy in cognitively normal older adults: systematic review and meta‐analysis

ConclusionsDifferent methodology to access TDP‐43, and also differences in lifestyle and genetic factors across different populations could explain our results. Standardization of TDP‐43 measurement, and future studies about the impact of genetic and lifestyle characteristics on the development of neurodegenerative diseases are needed.This article is protected by copyright. All rights reserved.

Source: Neuropathology and Applied Neurobiology - August 1, 2017 Category: Neurology Authors: Camila Nascimento, Ana Tereza Di Lorenzo Alho, Caroline Bazan Concei ção Amaral, Renata Elane Paraizo Leite, Ricardo Nitrini, Wilson Jacob‐Filho, Carlos Augusto Pasqualucci, Suvi Rosa Kastehelmi Hokkanen, Sally Hunter, Hannah Keage, Gabor G Kovacs, Le Tags: Original Article Source Type: research