Genomic plasticity between human and mycobacterial DNA: A review
Mycobacterium tuberculosis has a remarkable ability of long-term persistence despite vigorous host immunity and prolonged therapy. The bacteria persist in secure niches such as the mesenchymal stem cells in the bone marrow and reactivate the disease, leading to therapeutic failure. Many bacterial cells can remain latent within a diseased tissue so that their genetic material can be incorporated into the genetic material of the host tissue. This incorporated genetic material reproduces in a manner similar to that of cellular DNA.
Source: Tuberculosis - Category: Respiratory Medicine Authors: Lawal Danjuma, Mok Pooi Ling, Rukman Awang Hamat, Akon Higuchi, Abdullah A. Alarfaj, Marlina, Giovanni Benelli, Palanisamy Arulselvan, Mariappan Rajan, Suresh Kumar Subbiah Tags: Review Source Type: research
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