Detection of enrofloxacin after single-dose percutaneous administration in python regius, boa constrictor imperator, and acrantophis dumerili

In this study, the blood concentration of enrofloxacin administered transdermally to three different reptilian species, Python regius, Acrantophis dumerili, and Boa constrictor imperator at 50mg/kg was determined. The formulation used was a transdermal commercial vehicle, Pentravan ® cream, a hydrophilic base emulsion that uses the liposomal technique to penetrate the skin. The enrofloxacin was incorporated at 5wt % in the Pentravan® cream, and the plasma level of enrofloxacin and its metabolite ciprofloxacin were measured using high-performance liquid chromatography (HPLC).
Source: Journal of Exotic Pet Medicine - Category: Veterinary Research Authors: Source Type: research