A serologic study of related and unrelated food allergens in dogs

Cutaneous adverse food reactions (AFRs) are a common cause of nonseasonal pruritus in dogs and can result from both immunological and nonimmunological reactions. The immunological mechanisms involved in cutaneous AFRs are complex and poorly understood. Early studies did not support a role for IgE in the pathogenesis, but the diagnosis of AFR in these dogs was based upon a 3-week elimination diet trial as opposed to the 8 to 10 weeks now considered mandatory. Results of lymphocyte blastogenesis and patch testing in dogs with AFR have suggested a role for cell-mediated hypersensitivity.
Source: Advances in Small Animal Medicine and Surgery - Category: Veterinary Research Tags: Dermatology Source Type: research