The effect of metal ions released from different dental implant-abutment couples on osteoblast function and secretion of bone resorbing mediators

Conclusion Osteoblastic cell viability, apoptosis, and regulation of bone resorbing mediators were significantly altered in the presence of metal ions. The change in cytokine levels expressed was directly proportional to the metal ion concentration. Clinical significance The observed biological responses to decreased amounts of metal ions released from platform-switched implant-abutment couples compared to platform-matched couples may partly explain the positive radiographic findings in respect to crestal bone level when utilising the “platform-switching” concept, which highlights the possible role of corrosion products in the mediation of crestal bone loss around dental implants
Source: Journal of Dentistry - Category: Dentistry Source Type: research