Ensemble of Expert Deep Neural Networks for Spatio-Temporal Denoising of Contrast-Enhanced MRI Sequences

Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) of the brain is a noninvasive, in vivo tool to detect and quantify pathologies based on contrast agent (CA) accumulation (Tofts, 2005). The acquisition technique involves repeated T1 weighted imaging of tissues before, during and after the injection of a CA. The CA changes the tissue ’s T1 relaxation time (Tofts and Kermode, 1991), which manifests as signal enhancement (see Fig. 1). The frequency of MRI acquisitions (temporal sampling rate) in DCE-MRI should be sufficiently high to fully capture the dynamics of the CA.
Source: Medical Image Analysis - Category: Radiology Authors: Source Type: research