Loss of Y Chromosome in Blood Is Associated With Major Cardiovascular Events During Follow-Up in Men After Carotid Endarterectomy [Original Articles]

Conclusions—
In this hypothesis-generating study, LOY in blood is independently associated with secondary major cardiovascular events in a severely atherosclerotic population. Our data could indicate that LOY affects secondary outcome via other mechanisms than inflammation in the atherosclerotic plaque.

Source: Circulation: Cardiovascular Genetics - August 2, 2017 Category: Cardiology Authors: Haitjema, S., Kofink, D., van Setten, J., van der Laan, S. W., Schoneveld, A. H., Eales, J., Tomaszewski, M., de Jager, S. C. A., Pasterkamp, G., Asselbergs, F. W., den Ruijter, H. M. Tags: Inflammation, Genetics, Mortality/Survival, Atherosclerosis Original Articles Source Type: research