Distribution of antibodies to selected antigens of Pseudomonas aeruginosa in children and young adults with cystic fibrosis.

CONCLUSIONS: In the present study, the increased serum concentrations of IgG antibodies to P. aeruginosa antigens (AP, ELA and Exo-A) were found most often in the patients with chronic P.a. infection and in those in whom P.a. (especially mucoid type) was cultured at the time of the study. The clinical significance of the elevated antipseudomonal antibodies level in 19% of the patients never infected with P.a. is unclear and needs further investigation.
PMID: 24964236 [PubMed - in process]

Source: Pneumonologia i Alergologia Polska - June 28, 2014 Category: Respiratory Medicine Authors: Gaweł J, Pogorzelski A, Działek-Smętek E, Sochań B, Ligarska R, Lącka M, Mazurek H Tags: Pneumonol Alergol Pol Source Type: research