Functional assessment of sodium chloride cotransporter NCC mutants in polarized mammalian epithelial cells

In conclusion, this system allows the activity, cellular localization, and abundance of wild-type or mutant NCC to be examined in the same polarized mammalian expression system in a rapid, easy, and low-cost fashion.

Source: AJP: Renal Physiology - August 2, 2017 Category: Urology & Nephrology Authors: Rosenbaek, L. L., Rizzo, F., MacAulay, N., Staub, O., Fenton, R. A. Tags: INNOVATIVE METHODOLOGY Source Type: research