Surfactant replacement therapy reduces acute lung injury and collapse induration-related lung remodeling in the bleomycin model

In conclusion, reduction in surface tension was effective to stabilize alveoli linked with an attenuation of parameters of acute lung injury at D3 and collapse induration at D7. Hence, SRT modifies disease progression to collapse induration.

Source: AJP: Lung Cellular and Molecular Physiology - August 1, 2017 Category: Respiratory Medicine Authors: Steffen, L., Ruppert, C., Hoymann, H.-G., Funke, M., Ebener, S., Kloth, C., Mühlfeld, C., Ochs, M., Knudsen, L., Lopez-Rodriguez, E. Tags: RESEARCH ARTICLE Source Type: research