A missense mutation in Grm6 reduces but does not eliminate mGluR6 expression or rod depolarizing bipolar cell function

This article describes a mouse model of the human disease complete congenital stationary night blindness in which the mutation reduces but does not eliminate GRM6 expression and bipolar cell function, a distinct phenotype from that seen in other Grm6 mouse models.

Source: Journal of Neurophysiology - August 1, 2017 Category: Neurology Authors: Peachey, N. S., Hasan, N., FitzMaurice, B., Burrill, S., Pangeni, G., Karst, S. Y., Reinholdt, L., Berry, M. L., Strobel, M., Gregg, R. G., McCall, M. A., Chang, B. Tags: Research Articles Source Type: research