In vitro performance of a shape memory polymer foam-coated coil embolization device

Aneurysmal subarachnoid hemorrhage (aSAH), bleeding into the subarachnoid space in the brain due to intracranial aneurysm rupture, is marked by significant morbidity and mortality rates. Incidence of aSAH occurs in 9.7 –14.5 out of every 100,000 adults in the United States where at least 25% of patients die and approximately 50% of survivors are left with persistent neurological deficit [1]. Standard endovascular treatment of intracranial saccular aneurysms involves the delivery and implantation of embolization coil devices into the aneurysm to promote thrombus formation, tissue healing, and neointimal growth across the aneurysm neck [2].

Source: Medical Engineering and Physics - July 31, 2017 Category: Biomedical Engineering Authors: Anthony J. Boyle, Mark A. Wierzbicki, Scott Herting, Andrew C. Weems, Adam Nathan, Wonjun Hwang, Duncan J. Maitland Source Type: research