Cardiovascular disease: CRHR2 blockade prevents heart failure

Nature Reviews Drug Discovery 16, 530 (2017). doi:10.1038/nrd.2017.142 Author: Sarah Crunkhorn Despite improvements in the treatment of cardiovascular diseases, the prognosis of heart failure remains poor. To identify potential novel therapeutic targets, Tsuda et al. analyzed G-protein-coupled receptor (GPCR) expression in mouse cardiomyocytes 2 weeks following transverse aortic constriction (TAC) and identified markedly increased expression
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research