Cancer: RNA-based approaches target KRAS

Nature Reviews Drug Discovery 16, 529 (2017). doi:10.1038/nrd.2017.137 Author: Sarah Crunkhorn Activating mutations in the KRAS oncogene commonly occur in human tumours and are associated with cancer initiation, metastasis and poor prognosis. Despite significant effort, direct and specific therapeutic targeting of KRAS has so far proved elusive. Two new papers now report the use
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research