Sleep and Alzheimer ’s disease: A pivotal role for the suprachiasmatic nucleus?

Alzheimer ’s disease (AD), which accounts for most of the dementia cases, is, aside from cognitive deterioration, often characterized by the presence of non-cognitive symptoms. Society is desperately in need for interventions that alleviate the economic and social burden related to AD. Circadian dysrhythmia , one of these symptoms in particular, immensely decreases the self-care ability of AD-patients and is one of the main reasons of caregiver exhaustion. Studies suggest that these circadian disturbances form the root of sleep-wake problems, diagnosed in more than half of AD patients.
Source: Sleep Medicine Reviews - Category: Sleep Medicine Authors: Source Type: research