Four New Cases of Pediatric Thoracic Aortic Aneurysm (TAA) with Review of the Molecular Genetic Basis, Utilizing the Newly Published Consensus Nomenclature

The majority of thoracic aortic aneurysms (TAA) in the pediatric population are due to post repair etiology (iatrogenic). Although rare, underlying inheritable disease and congenital cardiac anomalies represent the most common non-iatrogenic cause of TAA among patients in this age group (1 –21years of age). Herein, we present a case series of aortic aneurysms with varying underlying etiology. We discuss the molecular genetic basis of these syndromes in conjunction with the radiological findings and histological description utilizing the newly published consensus criteria article.

Source: Cardiovascular Pathology - July 28, 2017 Category: Cardiology Authors: Shriprasad Deshpande, Adina Alazraki, Nasim Khoshnam, Diana Kantarovich, Pooya Hoseinzadeh, Camden Hebson, Ajay Bhatia, Lauren Schaffer, Elana Maccou, Bahig M. Shehata Tags: Original Article Source Type: research