Origin and regulation of a lung repair kit
Nature Cell Biology 19, 885 (2017).
doi:10.1038/ncb3585
Author: Jichao Chen
The lung undergoes a striking repair process in response to severe injuries such as influenza infection. A study now demonstrates that associated stem/progenitor cells are heterogeneous in nature and comprise subpopulations dominated by hypoxia/Notch or Wnt signalling. Modulation of this heterogeneity in favour of functional repair may have therapeutic value.
Source: Nature Cell Biology - Category: Cytology Authors: Jichao Chen Tags: News and Views Source Type: research