Feline leukocyte adhesion (CD18) deficiency caused by a deletion in the integrin β2 (ITGB2) gene

ConclusionsFeline LAD exhibits features similar to LAD in other species. However, clinical episodes in FLAD appeared milder allowing for an extended life expectancy under long‐term antimicrobial therapy, possibly due to an alternative, CD18‐independent T‐cell proliferation pathway.

Source: Veterinary Clinical Pathology - July 27, 2017 Category: Veterinary Research Authors: Thomas R. Bauer, Suzanne M. Pratt, Christina M. Palena, Karthik Raj, Urs Giger Tags: Original Research Source Type: research