Innate immunity: Alarmins rewire innate immunity in newborns

This study describes an important role for the endogenous alarmins S100A8 and S100A9 in protecting newborn infants from sepsis. Healthy newborns produce extremely high levels of S100 alarmins for the first five days of life; the authors found that these alarmins signal through TLR4 to

Source: Nature Reviews Immunology - July 27, 2017 Category: Allergy & Immunology Authors: Yvonne Bordon Tags: Research Highlight Source Type: research