Hacking DNA copy number for circuit engineering

Nature Genetics 49, 1164 (2017).
doi:10.1038/ng.3923

Authors: Feilun Wu & Lingchong You
DNA copy number represents an essential parameter in the dynamics of synthetic gene circuits but typically is not explicitly considered. A new study demonstrates how dynamic control of DNA copy number can serve as an effective strategy to program robust oscillations in gene expression circuits.

Source: Nature Genetics - July 27, 2017 Category: Genetics & Stem Cells Authors: Feilun Wu Lingchong You Tags: News and Views Source Type: research