VIP cortical conductors set the tone for chronic pain

Nature Neuroscience 20, 1037 (2017). doi:10.1038/nn.4609 Authors: Erika K Harding & Michael W Salter Loss of inhibition in a circuit in the primary somatosensory cortex that controls the activity of layer 5 neurons drives pain hypersensitivity. Restoring this inhibition resets the inhibitory–excitatory balance, producing analgesia.
Source: Nature Neuroscience - Category: Neuroscience Authors: Tags: News and Views Source Type: research