VIP cortical conductors set the tone for chronic pain
Nature Neuroscience 20, 1037 (2017).
doi:10.1038/nn.4609
Authors: Erika K Harding & Michael W Salter
Loss of inhibition in a circuit in the primary somatosensory cortex that controls the activity of layer 5 neurons drives pain hypersensitivity. Restoring this inhibition resets the inhibitory–excitatory balance, producing analgesia.
Source: Nature Neuroscience - Category: Neuroscience Authors: Erika K Harding Michael W Salter Tags: News and Views Source Type: research