Elevated serum concentrations of β-2-microglobulin are often found at the time of diagnosis of hemophagocytic lymphohistiocytosis in adults with lymphoid and myeloid malignancies

Conclusions: Elevated serum B2M level is a frequent finding at the time of hM-HLH diagnosis in adults. It seems to be a useful indicator of HLH for its early detection and evaluation afterward, as well as for immediate therapeutic intervention. Further prospective investigations answering the question whether serum B2M can be used as a prognostic factor in hM-HLH would be of interest.
Source: Acta Haematologica Polonica - Category: Hematology Source Type: research