Drugging the 'undruggable' cancer targets

Nature Reviews Cancer 17, 502 (2017).
doi:10.1038/nrc.2017.36

Authors: Chi V. Dang, E. Premkumar Reddy, Kevan M. Shokat & Laura Soucek
The term 'undruggable' was coined to describe proteins that could not be targeted pharmacologically. However, progress is being made to 'drug' many of these targets, and therefore more appropriate terms might be 'difficult to drug' or 'yet to be drugged'. Many desirable targets in cancer

Source: Nature Reviews Cancer - June 23, 2017 Category: Cancer & Oncology Authors: Chi V. Dang E. Premkumar Reddy Kevan M. Shokat Laura Soucek Tags: Perspectives Source Type: research