Epigenetics: Therapy-induced transcription is cryptically widespread

Nature Reviews Cancer 17, 456 (2017). doi:10.1038/nrc.2017.57 Author: Darren J. Burgess A new study demonstrates that DNA methyltransferase inhibitors and histone deacetylase inhibitors induce widespread cryptic transcription from transposable elements that may contribute to cancer immunogenicity.
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Research Highlight Source Type: research