Neuroblastoma: Tumours get super-enhanced

Nature Reviews Cancer 17, 455 (2017). doi:10.1038/nrc.2017.56 Author: Conor A. Bradley Van Groningen et al. unravel the epigenetic nature of intratumoural heterogeneity in neuroblastoma, which comprises both lineage-committed adrenergic cells and undifferentiated mesenchymal cells that are defined by unique super-enhancer transcriptional networks and gene expression signatures.
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Research Highlight Source Type: research