Neuroblastoma: Tumours get super-enhanced
Nature Reviews Cancer 17, 455 (2017).
doi:10.1038/nrc.2017.56
Author: Conor A. Bradley
Van Groningen et al. unravel the epigenetic nature of intratumoural heterogeneity in neuroblastoma, which comprises both lineage-committed adrenergic cells and undifferentiated mesenchymal cells that are defined by unique super-enhancer transcriptional networks and gene expression signatures.
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Conor A. Bradley Tags: Research Highlight Source Type: research
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